SCC antibody
| 产品别名 |
Serpin B3, also known as Squamous Cell Carcinoma Antigen-1 (SCCA1) |
| 免疫原 |
Human SCC |
产品参数
| 货号 |
SLS-113-03 |
| 克隆类型 |
S4-7 |
| 亚型 |
IgG1 |
| 规格 |
1mg/支 |
| 浓度 |
2-3mg/ml |
| 配对 |
This antibody can be used for solid phase coating when paired with SLS-113-04. |
| 纯度 |
>95% pure(SDS-PAGE). |
| 批号 |
随货见 |
| 状态和缓冲液 |
0.01M PBS, 0.9% NaCl, pH 7.4 |
使用建议 & 方法学
| 应用 |
This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using. |
| 使用建议 |
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. |
存储 & 安全
| 存储 |
Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles. |
产品描述
Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.
