Goat Anti-human IgM/FITC可申请样品试用
| 免疫原 |
Full length plasma protein |
产品参数
| 货号 |
SLS-EKKR-5430/FITC |
| 克隆类型 |
Polyclonal |
| 规格 |
2mg/ml |
| 状态和缓冲液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 浓度 |
2mg/1ml |
使用建议 & 方法学
| 使用建议 |
Flow-Cyt=1:100-1000 IF=1:100-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
存储 & 安全
| 存储 |
Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles. |
产品描述
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
